Vol. 5, Issue 2

Evaluation of musculoskeletal manifestations of hemoglobino-pathies by conventional imaging

Parthiv Brahmbhatt1, Srajan Dashore*2, Manoj Dholu2 , C. Raychaudhuri3

1Professor, 2Resident, 3Professor & HOD; Department of Radiology, SBKS Medical Institute & Research Centre, Sumandeep Vidyapeeth, Piparia, Waghodia, Vadodara, Gujarat, India



Introduction: The hemoglobinopathies are a group of genetic disorders in which there is alteration of hemoglobin structure. These hematologic disorders of the skeleton produce radiologic appearances related to marrow infiltration and/or replacement. Common findings are in place of such as osteopenia with trabecular prominence, growth disturbances, and extramedullary hematopoiesis. Conventional Radiography is required for knowing the imaging appearances of sickle cell disease, thalassemia, and other rare causes of anemia.

Objectives: To study the role of conventional imaging in detecting various radiological manifestations of hemaglobinopathies.

Materials & Methods: An observational descriptive study of 21 cases with hemaglobinopathies was done by conventional radiography & its varied  musculoskeletal manifestations were studied.

Result: Most common site of involvement was head of femur which was seen in 16 cases out of which isolated involvement was seen in 10 cases. Rest of the cases was associated with spine, skull and upper limb manifestations.

Conclusion: Knowledge of the distribution and site of involvement and its musculoskeletal features is of considerable diagnostic importance in the evaluation and treatment of hemoglobinopathies. Conventional Radiography is required and its primary investigation modality It is important to know the extent of the range of radiologic appearances in order to accurately diagnose complications and to provide appropriate treatment.

Keywords: Hemoglobinopathies, Conventional Radiography,