Seroprevalence of HIV, HBV, HCV & RPR in the cornea donor in the regional institute of ophthalmology
Patel MH*1, Patel AM2, Shah AM3
1Associate Professor, Department of Microbiology, M & J Institute of Ophthalmology, B J Medical College, Ahmedabad, Gujarat, India.
2Tutor, Department of Pathology & Microbiology, Govt. Dental College, Civil Hospital Campus, Ahmedabad , Gujarat, India
3Associate Professor, Department of Pathology, M & J Institute of Ophthalmology, B J Medical College, Ahmedabad, Gujarat, India .
Introduction: Donor corneas obtained by eye banks are steadily increasing all over the world. Proper evaluation of donor cornea is critical to the success of cornea transplantation.
Objectives: To analyse results of screening test done before corneal tissue transplantation. Methods: Blood samples were collected at the time of enucleation of the eye from 947 consecutive cornea donors. The samples were tested for Antibodies of Human Immunodeficiency virus I & II (HIV), Hepatitis B virus (HBV), and Hepatitis C virus (HCV) & Treponema pallidum.
Results: In our study sero-prevalence of HIV, HBV, HCV & T. pallidum in eye donors are 1.58%, 0.52%, 0.10 and 0.21% respectively. Conclusion: The study suggests that all the cornea donors should be screened for HIV, HBV, HCV & T. pallidum by serological test like standards followed in Blood banks of India.
Key words: Screening test, Cornea donors, Serological marker