Hs-CRP levels in patients with periodontitis- a cross sectional study
MA Shah1, BK Shah2, BB Modi2, EB Shah2, DH Dave3
1 Professor, Department of Periodontics, K M Shah Dental College, Sumandeep Vidyapeeth, Piparia, Vadodara. 391760, India 2 Senior Lecturer, Department of Periodontics, K M Shah Dental College, Sumandeep Vidyapeeth, Piparia, Vadodara. 391760, India 3 Professor & HOD, Department of Periodontics, K M Shah Dental College, Sumandeep Vidyapeeth, Piparia, Vadodara. 391760, India
Correspondence Address:
M A Shah Professor, Department of Periodontics, K M Shah Dental College, Sumandeep Vidyapeeth, Piparia, Vadodara. 391760 India
 Source of Support: None, Conflict of Interest: None  | 1 |
DOI: 10.4103/2347-6486.238514
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Background: During the last century, cardiovascular disease (CVD) has common occurrence in most of the population and the great attendant mortality, loss of independence, impaired quality life and social and economic costs forming a compelling reason for public health concern. C reactive protein (CRP) in particular has been the focuses of attention as a key marker of atherosclerosis and elevated level constitutes a risk predictor for CVD.
Aim: The present study focuses the association between periodontal inflammatory status as assessed by clinical periodontal sum score (CPSS) and levels of CRP and to co-relate periodontal destruction levels with levels of hs- CRP.
Methodology: Patients with chronic generalized periodontitis were selected. Periodontal destruction of the patient included in the study was recorded by CPSS and blood was tested for hs-CRP levels. Mean, Standard deviation and range of CPSS and hs-CRP were calculated. The correlation between CPSS and hs-CRP that is clinical index and biochemical marker was made by Spearman correlation test for significant.
Results: A total of 20 patients had participated in this study. The CPSS ranged from 31 to 205 and the hs-CRP levels ranged from 0.18 to 16.45. 2 tailed Spearman correlation test showed significant p value (0.05).
Conclusion: Statistical significant co-relation was found between periodontal disease as assessed by CPSS and hs-CRP level. Results of this study point to the importance of diagnosing cases of severe periodontal destruction, and the need for proper health education and prompt periodontal therapy for the cases identified.
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