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Extract of Euphorbia milii flower: A natural indicator in acid-base titration
K Trivedi Divya1, K Sureja Dipen2, P Sanghvi Kirtan3, P Shah Ashish3, K Seth Avinash4
1 Student, Department of Pharmacy, Sumandeep Vidyapeeth, Piparia, Waghodia, Vadodara, Gujarat, India
2 Associate Professor, Department of Pharmacy, Sumandeep Vidyapeeth, Piparia, Waghodia, Vadodara, Gujarat, India
3 Assistant Professor, Department of Pharmacy, Sumandeep Vidyapeeth, Piparia, Waghodia, Vadodara, Gujarat, India
4 HOD, Department of Pharmacy, Sumandeep Vidyapeeth, Piparia, Waghodia, Vadodara, Gujarat, India
Correspondence Address:
K Sureja Dipen
Associate Professor, Department of Pharmacy, Sumandeep Vidyapeeth, Piparia, Waghodia, Vadodara, Gujarat
India
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/2347-6486.240196
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Introduction: Synthetic indicators had continuously been the first choice for all types of acid-base titrations since long time. However, due to certain disadvantages like high cost, availability problems and environmental pollution, an attempt is required to replace synthetic indicators with natural indicators.
Methods: Methanolic extract of Euphorbia milii flowers from family Euphorbiaceae were evaluated in different types of titrations like strong acid (SA) v/s strong base (SB), weak base (WB) v/s strong acid (SA), and weak acid (WA) v/s strong base (SB).
Results: Natural indicators gives sharp and intense colour change at the neutralization point and shows promising results when tested against available synthetic acid-base indicators such as methyl orange and phenolphthalein.
Conclusion: This natural indicators could be an excellent replacement for synthetic indicators since they are economical, easily available, non-toxic, easy to extract, ecofriendly and accurate in all types of acid-base titrations.
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