| ORIGINAL ARTICLE |
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| Year : 2019 | Volume
: 7
| Issue : 1 | Page : 8-12 |
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Effect of systemic doxycycline on scaling and root planing in chronic periodontitis
Dhwani Vyas, Neeraj Chandrahas Deshpande, Deepak Dave
Department of Periodontology, K. M. Shah Dental College and Hospital, Sumandeep Vidyapeeth, Vadodara, Gujarat, India
Correspondence Address:
Dr. Neeraj Chandrahas Deshpande
K. M. Shah Dental College and Hospital, Sumandeep Vidyapeeth, Piparia, Waghodia, Vadodara - 391 760, Gujarat
India
 Source of Support: None, Conflict of Interest: None  | 2 |
DOI: 10.4103/JIHS.JIHS_4_18
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Background: Periodontitis is a multifactorial chronic inflammatory disease. It occurs due to inflammation and tooth-supporting tissues destruction by subgingival microbiota. Anti-infective therapy has been accepted as the cornerstone of periodontal treatment. Aim: The aim of the study was to evaluate the efficacy of doxycycline as adjunct to scaling and root planing in treatment of chronic periodontitis. Materials and Methods: A total of 52 participants having moderate to severe chronic periodontitis were included and divided into 2 groups: Group A (Test group-SRP+Doxycycline) and Group B (Control group-SRP alone). Plaque Index (PI), Gingival Index (GI), Probing Depth (PD) and Clinical Attachment Level (CAL) were assessed at baseline and 3 months interval. Result: Significant differences were seen from baseline to 3 months in both test and control groups in terms of reduction in PI, GI, PD and gain in CAL (P<0.001). Inter-group analysis showed significant differences between the two groups after 3 months, with GI, PD and CAL with P-value <0.001. Conclusion: At the end of 3 months, Doxycycline showed better results after mechanical therapy in the treatment of patients with chronic periodontitis because it has an anticollagenase effect that can inhibit tissue destruction and aid bone regeneration.
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