| CASE REPORT |
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| Year : 2021 | Volume
: 9
| Issue : 2 | Page : 122-124 |
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Epidermal growth factor receptor mutated lung cancer presenting as synchronous with a recurrent nonhuman papillomavirus-related head-and-neck squamous cell carcinoma
Daphne Fonseca1, Sahithi Shilpa Arya1, Vaishnavi Kunteepuram1, K V. V N. Raju2, Senthil Rajappa3
1 Department of Laboratory Medicine, Basavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, Telangana, India
2 Department of Surgical Oncology, Basavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, Telangana, India
3 Department of Medical Oncology, Basavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, Telangana, India
Correspondence Address:
Dr. Daphne Fonseca
Department of Laboratory Medicine, Basavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad - 500 034, Telangana
India
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/jihs.jihs_17_21
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A patient with nonhuman papillomavirus (HPV)-related head-and-neck cancers is at an increased risk of developing second primary malignancies. We present a case of non-HPV-related squamous cell carcinoma (SCC) of the left lower alveolus who presented with locoregional recurrence in the left upper lip 3 years after initial treatment with chemoradiotherapy along with a synchronous Epidermal growth factor receptor(EGFR)mutated lung adenocarcinoma. Comprehensive genomic profiling will guide diagnosis and therapy in these cases. Registry of synchronous tumors would help design protocols for better management.
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